S4TE2.0

S4TE-Doc

This software has been registered with the "Agence pour la Protection des Programmes (APP)" for version 1.0 under registration number IDDN.FR.001.310023.000.S.P.2012.000.31230, filled June 2012 and for version 1.4 under registration number IDDN.FR.001.310023.001.S.P.2012.000.31230, filled March 2016.

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S4TE 2.0

To help biologists to identify putative Type IV Effectors (T4Es) from complete bacterial genomes, we developed S4TE 2.0, an online bioinformatics suite of tools. S4TE 2.0 predicts and ranks candidate T4Es by using a combination of 14 sequence characteristics, including homology to known effectors, homology to eukaryotic domains, presence of subcellular localization signals or secretion signals, etc. S4TE 2.0 generates a score and sorts the best T4Es candidates.

S4TE-EM

S4TE-EM is a modular software and the user keeps the possibility to adjust various parameters such as the selection of search modules and the weight of each module.

S4TE-CG

S4TE-CG allows the comparison of putative T4Es repertoires among up to four bacterial strains. The software identifies T4Es orthologs between compared strains and returns the Venn diagram and a list of genes for each intersection.

S4TE-Doc

S4TE-Doc Everything you always wanted to know about S4TE 2.0

Citations:
Noroy C, Lefrançois T, and Meyer DF (2019). Searching Algorithm for Type IV Effector proteins (S4TE) 2.0 : improved tools for type IV effector prediction, analysis and comparison in proteobacteria. PLOS Computational Biology,15(3) : e1006847, first published online March 25, 2019 https://doi.org/10.1371/journal.pcbi.1006847

Meyer DF, Noroy C, Moumène A, Raffaele S, Albina E, Vachiéry N. (2013). Searching algorithm for type IV secretion system effectors 1.0 : a tool for predicting type IV effectors and exploring their genomic context. Nucleic Acids Research, 41 (20) : 9218-9229, first published online August 13, 2013, doi:10.1093/nar/gkt718

Frequently asked questions

Download S4TE 1.4 package S4TE1.4.zip

Please note that S4TE 2.0 is intended for academic user only. Other users are requested to contact S4TE Project Manager at sate@cirad.fr. Please do not redistribute S4TE in any form to other users. We prefer that all users download their own copy from the S4TE website directly in order to maintain a list of users.

S4TE 2.0 software and website were developed and designed by Christophe Noroy and Damien F. Meyer